y ordenado con Tac de abdomen, Videocolonofibroscopía normal, nos condujo a pensar en esta patología.
La cirugía practicada Hemicolectomía Oncológica, se realizó con anastomosis con sutura mecánica G.I.A, anastomosis latero – lateral y cierre terminal con cartucho recargable G.I.A 75 mm.
La Anatomía Patológica e Inmunohistoquímica confirmo “Tumor Estromal Benigno de Ciego”.
La recuperación de la paciente, aunque con complicaciones fue satisfactoria.
Bibliografía
1. Golden T, Stout AP. Smooth muscle tumours of the gastrointestinal tract and retroperitoneal tissues. Surg Ginecol Obstet 1941; 73: 784-810. [Links]
2. Stout AP. Bizarre smooth muscle tumours of stomach. Cancer 1976; 15: 400-9. [Links]
3. Herrera GA, Pinto DM, Grizzle WE, Han SG. Malignant small bowel neoplasm of enteric plexus derivation (plexosarcoma). Light and microscopic study confirm the origin of neoplasm. Dig Dis Sci 1984; 29: 275-84. [Links]
4. Manzur MT, Clark HB. Gastric stromal tumours. Reappraisal of histogenesis. Am J Surg Pathol 1983; 7: 507-19. [Links]
5. Hirota S, Isozaki K, Moriyama Y, Hashimoto K, Nishida T, Ishigmo S et al. Gain of function mutation of c kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-80. [Links]
6. Rubin BP, Fletcher JA, Fletcher CD. Molecular insights into the histogenesis and patogenesis of gastrointestinal stromal tumours. Int J Surg Pathol 2000; 8: 5-10. [Links]
7. Miettinen M, Lasota J. Gastrointestinal stromal tumours – definition, clinical, histological, inmunohistochemical and molecular genetic features and differential diagnosis. Virchows Arch 2001; 438: 1-12. [Links]
8. Nilson B, Bumming P, Meis-Kindblom JM, Oden A, Dortok A, Gustavsson B et al. Gastrointestinal stromal tumours: The incidence, prevalence, clinical course and pronostication in the pre imatinib mesylate era. Cancer 2005; 103: 821-9. [Links]
9. Goettsch WG, Bos SD, Breekveldt-Postma N, Casparie M, Herings RM, Hogendoorn PC. Incidence of gastrointestinal stromal tumours is understimated: Results of a nation-wide study. Eur J Cancer 2005; 41: 2868-72. [Links]
10. Tryggvason G, Gislason HG, Magnusson MK, Jonasson JG. Gastrointestinal stromal tumors in Iceland, 1990-2003: The Icelandic GIST study, a population based incidence and patologic risk stratification study. Int J Cancer 2005; 117: 289-93. [Links]
11. Carney JA. Gastric stomal sarcoma, pulmonary condroma and extra adrenal paraganglioma (Carney triad): Natural history, adreno cortical component and posible familial occurrence. Mayo Clin Proc 1999; 74: 543-52. [Links]
12. Cárdenas R, Tapia A, Riquelme R. Leiomiosarcoma colorrectal. Rev Chil Cir 1997; 49: 701-4. [Links]
13. Jensen C, Moyano L,Cúneo A, Abedrapo M, Bocic G, Garrido R et al. GIST de colon. Diagnóstico y factores pronóstico. Rev Chil Cir 2001; 53: 91-4. [Links]
14. Braghetto I, Parada F, Cardemil G, Csendes A, Fernández E, Korn O et al. Tumores gastrointestinales estromales (GIST): Experiencia del Servicio de Cirugía del Hospital Clínico de la Universidad de Chile entre 1999 y 2005. Rev Méd Chile 2007; 135: 551-7. [Links]
15. Vliagoftis H, Worobac AS, Metcalfe DD. The proto oncogen c-kit and c-kit ligand in human disease. J Allergy Clin Inmunol 1997; 100: 435-40. [Links]
16. Heinrich MC, Blanke CD, Druker BJ, Corless CL. Inhibition of kit tyrosine kinase activity: a novel molecular approach to the treatment ok kit positive malignances. J Clin Oncol 2002; 20: 1962-703. [Links]
17. Arber DA, Tamayo R, Weiss LM. Paraffin section detection of the c kit gene product (CD 117) in human tissues: value in the diagnosis of mast cell disorders. Hum Pathol 1998; 28: 498-504. [Links]
18. Liu FY, Ql JP, Wu AP. Clinicopathological and inmuno-histochemical analysis of gastrointestinal stromal tumor. World J Gastroenterol 2006; 12: 4161-5. [Links]
19. Bucher P, Villiger P, Egger JF, Buhler L, Morel PH. Management og gastrointestinal stromal tumours: from diagnosis to treatment. Swiss Med WKLY 2004; 134: 145-53. [Links]
20. Corless CL, Fletcher JA, Heinrich MC. Biology of gastrointestinal stromal tumors. J Oncol 2004; 22: 3813-25. [Links]
21. Maertens O, Preñen H, Debiec-Rychter M, Wozniak A, Sciot R, Pauwels P et al. Molecular patogenesis of meltiple gastrointestinal stromal tumours in NF1 patients. Human Molecular Genetics 2006; 15: 1015-23. [Links]
22. Joensuu H. Current perspectives on the epidemiology of gastrointestinal stromal tumours. EJC Supplements 2006; 4 Suppl: 4-9. [Links]